Breast Cancer Vaccine prevent reoccurrence of barest cancer

Vaccine that prevent re-occurrence of barest cancer:Mucin1 +Mannan (a type of sugar) complex when injected in to patient affected with breast cancer develops cellular immunity that prevents  reoccurrence of breast cancer. Brest cancer is one of most life threatening disease responsible for loss of women’s lives worldwide. It accounts to about 29.1 % of the total cancers, and 13.7% of lives lost just […]

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How to calculate Air changes per hour ACPH in what is CFM in AHU

What is air changes per hour What is CFM how they are related to cleanness of Pharmaceutical Manufacturing Aria What is ACPH, Air Changes per hour Importance of CFM and ACPH (air changes per hour). How ACPH is related to cleanness of room. How to calculate Air changes per hour ACPH in what is CFM in AHU Is it true […]

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Revalidation in pharmaceutical manufacturing when why to do Revalidation

Revalidation in pharmaceutical manufacturing its regulatory and general requirements. Validation in pharmaceutical is not only mandatory by law or regulation, but also it a is one of the method by which pharmaceutical quality assurance ensure that the drug manufactured in the firm will always meet the required quality standards. Validation is a process of collecting or gathering and documenting the […]

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USFD Guidelines WHO GMP Guidelines on Validation Requirments of Documents and Documentation

Which documents are required to be keep updated during a Validation or Qualification Activity?  As per USFDA Guidelines, WHO GMP guidelines on Validation Which documents are required to be updated for conducting a successful validation activity. 1: Validation master Plan, should cover the present validation activity schedule and its revalidation future plan. 2. All SOPS of equipment and Processes should […]

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Stem Cells use Cord blood stem cells treatment

Stem cell and regenerative medicine: What is stem cell therapy ? Which disease condition can be treated with stem cell therapy.There are certain cells in our body known as stem cells can differentiate in to many different organ tissue cells and connective tissues (pluripotent cells), which make stem cells one of great tool in regenerative medicine in fact it is looked […]

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Novel Drug siRNA that lowers hypercholesterolemia in patients with gene disorder heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD)

Novel drug for hypercholesterolemia which is a SiRNA is now approved by USFDA for heterozygous familial hypercholesterolemia associated with genetic disorder (inclisiran)  injection of Novartis a silensing RNA inhibits the process of translation of protein so that faulty enzyme production stops which is responsible for lipid production and hyperlipidemia Basic constituent of the human body is a cell while proteins and […]

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First autoimmun antibody diagnostic test for type 1 diabetes.

ELISA Immunoassay test in detection of ZnT8Ab antibodies (zinc transporter 8 autoantibody) for diagnosis of Type 1 Diabetes. Type 1 diabetes is a form of diabetes which is one of very severe form of diabetes, wherein patients body do not produce insulin, or if at all it do is in very low amount. Insulin is the hormone responsible for mobilisation […]

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Monoclonal Antibodies found to be reducing occurrence of migraine

There is very little treatment options available for migraine and often those are not so effective in all patients unlike like other disease treatment involves lot of change overs in medications. A protein called calcitonin gene–related peptide (CGRP)is responsible for migraine. Hence to prevent the occurrence of migrane monoclonal antibodies which target this peptide was studied and found thatMonoclonal antibody […]

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Validation in Pharmaceutical Industry Types of Pharma Validation

Pharmaceutical validation In pharmaceutical manufacturing industry Pharma Validation regulatory requirements. Validation in Pharma Industry is very important part of Pharmaceutical Quality Management System which in turn constitute quality assurance systems and intern Good manufacturing Practice guidelines. US FDA have given special emphasis on validation and it is prime requirement of US FDA pre-qualification, as well as all other pharma industry […]

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Pharmaceutical Area classification with respect to filters used as per WHO guidelines

Pharmaceutical Area classification with respect to filters used as per WHO guidelines WHO gmp guidelines describes area in a pharmaceutical Manufacturing facility, as Level 1 level 2 and level 3 areas. Level 1 Area is a place where there is no possibility of contamination of product. Level 2 Area is an area where the raw and packing material is stored […]

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