Category: Pharmaceutical Manufacturing

Camera system for Blister Packing

Camera system for Blister packing Machine. How camera system works on blister packing ? Camera system in tablet blister packing machine is a system capable of identifying black spotted tablets, broken tablet, and unfilled pockets, or any other defective tablet, when the defective tablet or capsule goes in pocket of the blister, camera identifies these […]

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Clean Room Validation Recovery test

How a recovery test is done during validation of AHU/clean room in pharmaceutical manufacturing? Recovery test in AHU or clean room validation is a test where the ability of the clean room or AHU to maintain the level of cleanliness or the particle count below the rated classification limit. In the process clean room is […]

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Clean Room Validation Microbial Count Limits

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Microbial action limits for clean room

Clean Room Validation Microbial Count Limits method settle plate contact plate viable bacterial fungal count limits frequency of validation. Classification of clean rooms in pharmaceutical manufacturing companies is part of validation activity, a clean room is designed to provide the desired level of clean grade environment. but it’s rated only to a particular grade after […]

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Metal detector to remove metal particle tablets during manufacturing

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Metal detector system to eliminate metal particle containing tablets during manufacturing. Question: How to remove metal particles if any which might be getting generated during manufacturing due to wear and tear of machines. Answer: Source for Metal particles in a tablet dosage form may be one of following. Raw material, Defective equipment, like broken sieve […]

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Tablet dosage form defects solving the problem

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Question: How to solve this problem of Capping in tablets, we are getting consistent problem of capping in our Paracetamol tablets where paracetamol is 500 mg and other excipients like starch, and talcum, and aerosil, magnesium stearate etcetera comprises about 60 mg. The Total weight of the tablet is 560 mg. It is round beveled […]

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Document Control System in a Pharmaceutical Company

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Documentation control In a Pharmaceutical Manufacturing Company  Standard operating procedure is the originator of the documents, in a standard operating procedure instructions are provided for doing an activity. In the same SOP a format is provided for monitoring the parameters of the activity with time etc. This is there in the SOP at the end […]

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