Month: January 2023
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Drugs Causing Birth Defects
Drug that causes birth defects. Birth defects are caused when pregnant women take medicines listed below and various other unknown reasons. There are some medicines which are necessary for some women. They must take medicine for maintaining health. For example medicines for asthma and epilepsy cannot be stopped. But the very same medicines can cause…
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Camera system for Blister Packing
Camera system for Blister packing Machine. How camera system works on blister packing ? Camera system in tablet blister packing machine is a system capable of identifying black spotted tablets, broken tablet, and unfilled pockets, or any other defective tablet, when the defective tablet or capsule goes in pocket of the blister, camera identifies these…
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Clean Room Validation Recovery test
How a recovery test is done during validation of AHU/clean room in pharmaceutical manufacturing? Recovery test in AHU or clean room validation is a test where the ability of the clean room or AHU to maintain the level of cleanliness or the particle count below the rated classification limit. In the process clean room is…
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Clean Room Validation in Pharmaceutical Industry how to do
Clean Room Validation how it’s done different requirements of clean Room Validation from particle Count to Microbial Count Limits methods to do it? Validation is an important activity in Pharmaceutical Industry, it impart trust on the process and inturn the product manufactured. For doing validation of clean room, unless all the installed equipment are validated,…
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Clean Room Validation Microbial Count Limits
Clean Room Validation Microbial Count Limits method settle plate contact plate viable bacterial fungal count limits frequency of validation. Classification of clean rooms in pharmaceutical manufacturing companies is part of validation activity, a clean room is designed to provide the desired level of clean grade environment. but it’s rated only to a particular grade after…
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Tablet dosage form defects solving the problem
Question: How to solve this problem of Capping in tablets, we are getting consistent problem of capping in our Paracetamol tablets where paracetamol is 500 mg and other excipients like starch, and talcum, and aerosil, magnesium stearate etcetera comprises about 60 mg. The Total weight of the tablet is 560 mg. It is round beveled…
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Document Control System in a Pharmaceutical Company
Documentation control In a Pharmaceutical Manufacturing Company Standard operating procedure is the originator of the documents, in a standard operating procedure instructions are provided for doing an activity. In the same SOP a format is provided for monitoring the parameters of the activity with time etc. This is there in the SOP at the end…
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How to reduce cholesterol medicines for increased cholesterol
How to reduce cholesterol? Why medicines are used to Lower high cholesterol ? Which medicines are given to treat hypercholesterolemina ? Higher level of cholesterol in body is very dangerous as it may block coronary arteries and may cause heart failure, cholesterol tend to form fatty plaques in veins and arteries, which when dislodged may occlude blood…
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Live bacteria Virus used for treatment of diseases
Do you know that there are some diseases which can only be treated by injecting live bacteria and virus at the point of disease. Bladder Cancer treatment with live atenuated microorganisms Bacillus Calmette-Guerin (BCG). Gene Therapy assited by live virus vector, Novel Drug Delivery System. One of such disease is bladder cancer which is treated…
Guidelines on Pharmaceutical Manufacturing Pharma Quality Assurance Quality Management System 